Programmed macromolecular synthesis in regenerating karyoplasts.

Programmed macromolecular synthesis in regenerating karyoplasts.

Conditions for the preparation, purification, and maintenance of karyoplasts which could regenerate to reform whole viable cells were defined. Results of biochemical analyses of such karyoplasts at various times during regeneration indicated that a reproducible biosynthetic program was followed. Thus, an examination of the polypeptides made during regeneration by two-dimensional gel electrophor...

Macromolecular synthesis in cells infected with Herpes simplex virus

Control of Macromolecular Synthesis

It is indeed a privilege to read the life's work of an extremely competent investigator. This is the case with respect to Max Lurie's work, Resistance to Tuberculosis. The book is written in a most logical, clear and concise fashion. Each series of experiments follows one another as carefully planned building blocks to a most logical conclusion. It is difficult to "put this book down" as the re...

macromolecular synthesis in cells infected with herpes simplex virus

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Nicotinamide nucleotide synthesis in regenerating rat liver.

1. The concentrations and total content of the nicotinamide nucleotides were measured in the livers of rats at various times after partial hepatectomy and laparotomy (sham hepatectomy) and correlated with other events in the regeneration process. 2. The NAD content and concentration in rat liver were relatively unaffected by laparotomy, but fell to a minimum, 25 and 33% below control values res...